Licentiate thesis: Hydrogel based pH-sensors Development and characterization pH sensors based on stimuli-responsive hydrogels Date: Tuesday March 19,

This enhanced control has enabled groundbreaking advances in healthcare, allowing for more effective treatment of a vast array of diseases and improved approaches for tissue engineering and wound healing. The complex tissue‐specific physiology that is orchestrated from the nano‐ to the macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying biological processes, has inspired the design of sophisticated hydrogels and nanoparticle systems exhibiting stimuli‐responsive features. Recently, hydrogels and nanoparticles have been combined in advanced nanocomposite hybrid platforms expanding their range of biomedical applications. This Review presents polysaccharides, oligosaccharides, nucleic acids, peptides, and proteins as functional stimuli‐responsive polymer scaffolds that yield hydrogels with controlled stiffness. Different physical or chemical triggers can be used to structurally reconfigure the crosslinking units and control the stiffness of the hydrogels.

Hydrogels are swellable polymeric materials, and are being widely investigated as a carrier for drug delivery systems. Besides exhibiting swelling-controlled drug release, hydrogels also show stimuli responsive changes in their structural network and hence leading to the drug release. From this context, stimuli-responsive hydrogels are highly attractive as surrogate materials that can simulate dynamic physical microenvironments in vivo. Stimuli-responsive hydrogels formed by various natural and synthetic polymers are capable of showing distinctive changes in their properties with external stimuli like temperature, pH, light, ionic Notably, the hydrogels are highly sensitive to external stimuli, wherein gel–sol transition can be reversibly controlled by using temperature, pH and host–guest interaction. The integration of stimuli‐responsive supramolecular complexes and stimuli‐responsive biomolecular units as crosslinkers leads to hybrid hydrogels undergoing reversible triggered transitions across different stiffness states. Different applications of stimuli‐responsive biomolecule‐based hydrogels are discussed.

Stimuli‐Responsive Biomolecule‐Based Hydrogels and Their Foto. Glycogen synthase kinase-3: The missing link to aberrant Foto. Gå till. Connexin 43 and

Stimuli-responsive hydrogels are a class of materials that undergo a chemical transformation—and subsequent expansion or contraction—under the influence of a specific external stimulus. Keywords: smart hydrogels, stimuli-responsive hydrogels, controlled release, drug delivery systems, anticancer drug delivery systems Introduction The first mention of hydrogels appeared in the literature at the beginning of the 19th century; they have been described as colloidal gels derived from inorganic salts. Fabrication of multi-stimuli responsive supramolecular hydrogels based on host–guest inclusion complexation of a tadpole-shaped cyclodextrin derivative with the azobenzene dimer † Xing Wang, ‡ a Juan Wang, ‡ a Yanyu Yang,ab Fei Yang ab and Decheng Wu *ab Polyglycerol-based hydrogels from biodegradable raw materials were synthesized by crosslinking reactions of polyglycerol with citric and fatty acids. Three hydrogels were studied varying molar ratios of crosslinking agent.

Stimuli-responsive conductive hydrogel has been emerged as a new surging concept in hydrogel research field due to its combined advantages of stimuli-responsivity and conductivity from conductive

In addition, stimuli-sensitive hydrogels have the unique property of undergoing abrupt volume changes from their collapsed and swollen states in response to environmental stimuli, which have both sensor and effector functions. This Review presents polysaccharides, oligosaccharides, nucleic acids, peptides, and proteins as functional stimuli‐responsive polymer scaffolds that yield hydrogels with controlled stiffness. Different physical or chemical triggers can be used to structurally reconfigure the crosslinking units and control the stiffness of the hydrogels. 2020-12-01 2014-07-21 Collectively, recent breakthroughs in the design of stimuli‐responsive nanocomposite hydrogels improve their potential for operating as advanced systems in different biomedical applications that Hydrogels that Respond to Other Stimuli Hydrogels can be responsive to a vast array of other stimuli. Certain chemicals can be used as target molecules making the hydrogels either swell or degrade, either through direct interaction or indirectly through triggering … One strategy that has gained much attention in the last decades is the understanding and further mimicking of structures and behaviours found in nature, as inspiration to develop materials with additional functionalities. This review presents recent advances in stimuli-responsive gels with emphasis on functional hydrogels and microgels.

The hydrogel with the highest swelling capacity absorbed more Fast stimuli-responsive hydrogels based on natural and synthetic polymers, temperature responsive membranes and selective adsorbents were produced and Stimulus-responsive hydrogels have been especially impactful, allowing for unprecedented levels of control over material properties in response to external Abstract: This study describes stimuli-responsive hydrogel micro-actuators for compressive/expanding actuation of stimuli-responsive hydrogels. Inspired by Stimuli-responsive hydrogels formed by various natural and synthetic polymers are capable of showing distinctive changes in their properties with external 25 Dec 2019 Sciendo provides publishing services and solutions to academic and professional organizations and individual authors. We publish journals Stimuli-responsive hydrogels formed by various natural and synthetic polymers are capable of showing distinctive changes in their properties with external 17 Jun 2016 University of Hull | 06791 | P27 Stimuli-Responsive Hydrogels REEVE D'SOUZA © Kathy F. Atkinson. 27 Mar 2017 Responsive synthetic materials can translate environmental stimuli into a direct material response, for example thermo-responsive shape 31 Mar 2021 (D) Stimuli-responsive hydrogel coated with a layer of impermeable elastomer ( i.e., the asymmetric stimuli-responsive material) senses the 26 Jul 2018 Instead, polymer materials responsive to multiple physical or chemical stimuli are highly desired for biomedical applications (e.g., drug delivery). 6 May 2013 Recently the ability to utilize external stimuli to mimic the dynamic character of natural ECMs has been explored. The scope of this paper is to 11 Apr 2016 A series of lectures featuring materials sciences expert Professor Rigoberto Advincula of Case Western Reserve University!
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407-452. Many kinds of stimuli-responsive polymer gels that respond to the change in their surroundings such as solvent composition, temperature, pH, and supply of electric field have been developed. They are of interest as intelligent (or smart, biomimetic) materials which have sensor, processor, and actuator functions. Good cytocompatibility of the conductive hydrogels was also evaluated with L929 fibroblast cells.
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Protokoll för 3D Bioprinning av gelatin Methacryloyl hydrogel of multi-stimuli responsive graphene oxide composite hydrogel fibres by

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self-assembly of a stimuli-responsive peptide-hyaluronan hybrid hydrogel Degradation of the hydrogels can also be time-programed by encapsulation of a

The basic feature of this system is the ability to change their mechanical properties, swelling ability, hydrophilicity, bioactive molecules permeability, etc., influenced by various stimuli, such as temperature, pH, electromagnetic radiation, magnetic field and biological factors. Polyglycerol-based hydrogels from biodegradable raw materials were synthesized by crosslinking reactions of polyglycerol with citric and fatty acids. Three hydrogels were studied varying molar ratios of crosslinking agent.

Tough Stimuli-Responsive Supramolecular Hydrogels with Hydrogen-Bonding Network Junctions tough hydrogels include a strong, yet reversible interaction within segregated nanoscopic domains.35 Moreover, molecular architecture has a dramatic eﬀect on properties in PEG-based

6 May 2013 Recently the ability to utilize external stimuli to mimic the dynamic character of natural ECMs has been explored. The scope of this paper is to 11 Apr 2016 A series of lectures featuring materials sciences expert Professor Rigoberto Advincula of Case Western Reserve University! With considerable 14 Sep 2015 Stimuli-responsive hydrogels have attracted increasing interest due to their potential application in the biomedical field, for example as drug Figure 1: a) Previous stimuli-responsive (SR) hydrogel actuators: i) isotropic movement and ii) bending movement. b) Our proposal method: We proposed a 25 Feb 2013 Molecular Design of Stimuli Responsive Polymers Stephen Craig, Duke material (mechanical properties) in a variety of contexts: fluids, gels, 25 Dec 2019 Sciendo provides publishing services and solutions to academic and professional organizations and individual authors. We publish journals Stimuli-responsive polymers are defined as high-performance polymers that can change in accordance with the environment they are subjected to.

The abilities of intelligent polymer hydrogels to change their structure and volume phase in response to external stimuli have provided new possibilities for various advanced technologies and great research and application potentials in the medical field. Stimuli-responsive hydrogel membranes coupled with biocatalytic processes. Tokarev I, Gopishetty V, Zhou J, Pita M, Motornov M, Katz E, Minko S. A nanostructured signal-responsive thin hydrogel membrane was coupled with enzyme-based systems to yield "smart" multisignal-responsive hybrid systems with built-in "logic". Finally, special attention is focused on a new generation of functional stimuli-responsive polymer hydrogels able to self-shape (shape-memory) and/or self-repair.